Figure 2.

2-h cold exposure modifies the levels of signaling lipids

Effects of 2-h cold exposure on the plasma levels of omega-6 oxylipins (A), omega-3 oxylipins (B), endocannabinoids and analogs (eCBs, C), and lysophospholipids and sphingosine-1-phosphate (D) in young adults. The colors of the squares represent the mean log2 fold change of the area peak ratio of that time point relative to baseline. Red color represents an increase, whereas blue represents a decrease. p values were obtained from repeated measures analyses of variance (ANOVA). Values in brackets represent the percentage of change at 120 min relative to baseline. The name and abbreviations of signaling lipids are detailed in Table S3.