Figure 3.

Association between cold-induced changes in the plasma levels of signaling lipids and brown adipose tissue-related outcomes

Volcano plots show partial correlation analyses between the 120-min fold change relative to baseline and BAT volume (A), BAT SUVmean (B), BAT SUVpeak (C), and BAT mean radiodensity (D, n = 47). Partial correlation analyses were adjusted for the natural calendar day when the baseline PET/CT scan was performed. The X axis represents Pearson partial correlation coefficients, whereas the Y axis represents the false discovery rate (FDR)-adjusted p values of the correlations. Gray dots represent non-significant correlations, whereas colored dots represent statistically significant correlations (p value < 0.05 after FDR correction). Abbreviations are as follows: BAT, brown adipose tissue; eCBs, endocannabinoids; SUV, standardized uptake value.