REAGENT or RESOURCE | SOURCE | IDENTIFIER |
---|---|---|
Deposited data | ||
eQTLs | Genotype-Tissue Expression (GTEx) project18 | www.gtexportal.org/home/ |
GWAS of sex-combined HF | Heart Failure Molecular Epidemiology for Therapeutic Targets (HERMES) Consortium10 Global Biobank Meta-analysis Initiative (GBMI)19 |
www.nature.com/articles/s41467-019-13690-5 www.globalbiobankmeta.org/ |
GWAS of sex-stratified HF | Global Biobank Meta-analysis Initiative (GBMI)19 | www.globalbiobankmeta.org/ |
GWAS of sex-stratified LVEF | UK Biobank20 This study |
www.ukbiobank.ac.uk/ |
GWAS of male-dominate HFrEF and HFpEF | Million Veteran Program (MVP)11 | www.nature.com/articles/s41467-022-35323-0 |
Software and algorithms | ||
MR models | Hemani et al.83 | github.com/MRCIEU/TwoSampleMR |
LD check | Zhao et al.38 | github.com/globalbiobankmeta/multi-ancestry-pwmr |
LDSC | Ning et al.84 | github.com/bulik/ldsc |
R | Open source | https://www.r-project.org/ |
Other | ||
Variant Effect Predictor (VEP) | McLaren et al.85 | useast.ensembl.org/ |
Therapeutic Target Database | Zhou et al.34 | db.idrblab.net |
OpenTarget | Koscielny et al.33 | https://platform.opentargets.org/ |
ClinicalTrials | Open source | https://clinicaltrials.gov/ |