Table 1.

Pharmacologic dosing algorithm for deep venous thrombosis prophylaxis

Creatinine clearance, mL/min	Low actual body weight∗	BMI ≤ 39.9	BMI ≥ 40
≥ 30	Preferred: Heparin 5000 U every 12 h If benefits outweigh risks: Enoxaparin 30 mg daily	Heparin 5000 U every 8 or every 12 h Or Enoxaparin 40 mg daily	Heparin 7500 U every 8 h Or Enoxaparin 40 mg every 12 h
20-29.9	Preferred: Heparin 5000 U every 12 h If benefits outweigh risks: Enoxaparin 30 mg daily	Heparin 5000 U every 8 or every 12 h Or Enoxaparin 30 mg daily	Heparin 7500 U every 8 h Or Enoxaparin 40 mg daily
<20 or dialysis	Heparin 5000 U every 12 h	Heparin 5000 U every 8 or every 12 h	Heparin 7500 U every 8 h

BMI, Body mass index.

^∗Women <45 kg, men <57 kg.