Table 1.
Demographic and clinical characteristics before and after March 11, 2020∗
| Variable | Pre–COVID-19 era |
COVID-19 era |
Total |
P value |
|---|---|---|---|---|
| N = 3463 | N = 4014 | N = 7477 | ||
| Age, y, mean (SD) | 47.9 (15.2) | 48.2 (13.1) | 48.0 (14.1) | .48 |
| Race | <.001 | |||
| White | 2133 (61.6%) | 1750 (43.6%) | 3883 (51.9%) | |
| Black | 568 (16.4%) | 693 (17.3%) | 1261 (16.9%) | |
| Hispanic | 346 (10.0%) | 1067 (26.6%) | 1413 (18.9%) | |
| Asian | 67 (1.9%) | 129 (3.2%) | 196 (2.6%) | |
| Middle Eastern or North African | 22 (0.6%) | 40 (1.0%) | 62 (0.8%) | |
| Native American | 45 (1.3%) | 92 (2.3%) | 137 (1.8%) | |
| Native Pacific Islander | 9 (0.3%) | 14 (0.3%) | 23 (0.3%) | |
| Multiple | 215 (6.2%) | 167 (4.2%) | 382 (5.1%) | |
| Other | 58 (1.7%) | 62 (1.5%) | 120 (1.6%) | |
| Sex | <.001 | |||
| Female | 1356 (39.2%) | 1284 (32.0%) | 2640 (35.3%) | |
| Male | 2107 (60.8%) | 2730 (68.0%) | 4837 (64.7%) | |
| Weight | 96.1 (32.6) | 98.7 (27.8) | 97.5 (30.1) | <.001 |
| Year | <.001 | |||
| 2019 | 2691 (77.7%) | 0 (0.0%) | 2691 (36.0%) | |
| 2020 | 772 (22.3%) | 3496 (87.1%) | 4268 (57.1%) | |
| 2021 | 0 (0.0%) | 518 (12.9%) | 518 (6.9%) | |
| COVID-19 positive | <.001 | |||
| No | 3461 (99.9%) | 1237 (30.8%) | 4698 (62.8%) | |
| Yes | 2 (0.1%) | 2777 (69.2%) | 2779 (37.2%) | |
| Rate | 23.4 (7.4) | 25.6 (7.1) | 24.6 (7.3) | <.001 |
| FiO2 | 93.1 (15.3) | 94.0 (13.1) | 93.6 (14.2) | .018 |
| pH | 7.25 (0.13) | 7.27 (0.13) | 7.26 (0.13) | <.001 |
| PCO2 | 63.0 (30.6) | 66.2 (30.2) | 64.8 (30.4) | <.001 |
| PO2 | 99.9 (102.2) | 89.2 (85.0) | 94.1 (93.3) | <.001 |
| HCO3 | 25.4 (6.9) | 28.0 (7.2) | 26.8 (7.2) | <.001 |
| SaO2† | 90.0 (83.0-95.0) | 91.0 (85.0-95.0) | 91.0 (84.0-95.0) | .016 |
| Renal/pulmonary/other support | 1503 (43.4%) | 2551 (63.6%) | 4054 (54.2%) | <.001 |
| Vasoactives used | 2105 (60.8%) | 2264 (56.4%) | 4369 (58.4%) | <.001 |
| Pre-ECLS arrest | <.001 | |||
| No | 3018 (87.1%) | 3725 (92.8%) | 6743 (90.2%) | |
| Unknown | 43 (1.2%) | 34 (0.8%) | 77 (1.0%) | |
| Yes | 402 (11.6%) | 255 (6.4%) | 657 (8.8%) |
FiO2, Fraction of inspired oxygen; HCO3, bicarbonate; SaO2, oxygen saturation; ECLS, extracorporeal life support.
∗
Unless indicated as a percentage, values within parentheses represent SDs.
†
Nonparametric test used, and value is median with interquartile range.