Table 4:
Proportion of participants with seropositivity and geometric mean titres for anti-circumsporozoite antibodies
| N | ≥0·5 EU/mL | GMT (95% CI) | |
|---|---|---|---|
|
| |||
| RTS,S/AS01 vaccine | |||
| Screening | 81 | 16 (20%), 11·7–30·1 | 0·3 (0·3–0·4) |
| 1 month after dose 3 | 79 | 79 (100%), 95·4–100 | 329·2 (260·6–415·8) |
| 12 months after dose 3 | 73 | 72 (99%), 92·6–100 | 18·4 (13·3–25·5) |
| Rabies vaccine | |||
| Screening | 73 | 13 (18%), 9·8–28·5 | 0·3 (0·3–0·4) |
| 1 month after dose 3 | 71 | 9 (13%), 6·0–22·7 | 0·3 (0·3–0·3) |
| 12 months after dose 3 | 67 | 6 (9%), 3·4–18·5 | 0·3 (0·3–0·3) |
Data are n (%), 95% CI, or geometric mean antibody titre (GMT; 95% CI) taken from the according-to-protocol population for immunogenicity. EU=enzyme-linked immunosorbent assay unit. N=number of children with available results.