Table 2:

Evolutionary forces relevant to modelling load and how these forces impact load

Evolutionary force	Impact on genetic load	Impact on inbreeding load
Population size ($N$)	Decrease with increasing $N$	Increase with increasing $N$
Mutation rate ($\mathrm{\mu }$)	Increase with increasing $\mathrm{\mu }$	Increase with increasing $\mathrm{\mu }$
Deleterious mutation target size ($G$)	Increase with increasing $G$	Increase with increasing $G$
Distribution of fitness effects ($s$)	Depends on N*	Increase with increasing mean $s$
Dominance distribution ($h$)	Increase as $h$ increases from 0 to 0.5	Decrease as $h$ increases from 0 to 0.5
Recombination rate ($r$)	Decrease with increasing $r$	Decrease with increasing $r$

^*Note that, under classical models of mutation load due to mutations segregating under mutation-selection balance, $s$ does not impact load. However, this result does not hold when considering fixed mutations and finite population size. See Kimura 1963 for a detailed analysis of the effects of $s$, $h$, and $N$ on genetic load.