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. Author manuscript; available in PMC: 2024 Dec 1.
Published in final edited form as: Am Nat. 2023 Oct 27;202(6):737–752. doi: 10.1086/726736

Table 3:

Comparison DFE, dominance, and mutation rate parameters

Model mean s shape lethals mean h U

Kyriazis et al. 2021 0.0131 0.186 0 0.18 0.42
Kardos et al. 2021 0.05 0.1 5% 0.31 1.2
Pérez-Pereira et al. 2022 0.2 0.33 0 0.28 0.4
This study 0.0131 0.186 0.3% 0.28 0.63

Note that the mean s and shape are for parameterizing a gamma distribution and “lethals” denotes an additional proportion of recessive lethals augmented to the gamma distribution. Mean h denotes the mean dominance coefficient for new mutations under each DFE (note that this value is impacted by the assumed DFE, as DFEs with more strongly deleterious mutations will tend to have a more recessive mean h when keeping the distribution of h constant). U represents the diploid genomic deleterious mutation rate from each of these models.