Table 3:
Comparison DFE, dominance, and mutation rate parameters
| Model | mean | shape | lethals | mean | |
|---|---|---|---|---|---|
|
| |||||
| Kyriazis et al. 2021 | 0.0131 | 0.186 | 0 | 0.18 | 0.42 |
| Kardos et al. 2021 | 0.05 | 0.1 | 5% | 0.31 | 1.2 |
| Pérez-Pereira et al. 2022 | 0.2 | 0.33 | 0 | 0.28 | 0.4 |
| This study | 0.0131 | 0.186 | 0.3% | 0.28 | 0.63 |
Note that the mean and shape are for parameterizing a gamma distribution and “lethals” denotes an additional proportion of recessive lethals augmented to the gamma distribution. Mean denotes the mean dominance coefficient for new mutations under each DFE (note that this value is impacted by the assumed DFE, as DFEs with more strongly deleterious mutations will tend to have a more recessive mean when keeping the distribution of constant). represents the diploid genomic deleterious mutation rate from each of these models.