Table 3 –
Summary GABA+ estimates from the GABA-edited spectra. Significant differences between the healthy control and the HE group and significant correlations between the clinical metrics and the GABA+ levels are indicated in bold. Comparisons and correlations were corrected for multiple comparisons using the Benjamini-Hochberg procedure with an FDR of 0.05.
| mean (SD) | weighted partial correlation r | |||||
|---|---|---|---|---|---|---|
| controls | mHE | HE | CFF | tPEG score | NH3 | |
| Cerebellum | ||||||
| GABA+/tCr | 0.10 (.01) | 0.10 (.01) | 0.12 (.01) | −0.27 | 0.43 | 0.11 |
| GABA+ (i.u) | 4.85 (.45) | 5.62 (1.95) | 5.32 (.48) | −0.05 | 0.04 | −0.04 |
| Thalamus | ||||||
| GABA+/tCr | 0.10 (.02) | 0.11 (0.04) | 0.10 (0.02) | −0.47 | 0.13 | −0.11 |
| GABA+ (i.u) | 4.27 (.79) | 4.42 (1.06) | 4.46 (0.88) | −0.30 | 0.26 | −0.21 |
| Motor cortex | ||||||
| GABA+/tCr | 0.11 (.01) | 0.09 (0.01) | 0.09 (.01) | 0.65 | −0.65 | 0.18 |
| GABA+ (i.u) | 3.91 (.16) | 3.31 (.27) | 2.86 (.51) | 0.73 | −0.65 | −0.05 |