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. 2024 Feb 26;331(12):1057–1059. doi: 10.1001/jama.2024.1036

Table. Cohort Characteristics in a Study of XBB.1.5-Containing Vaccinesa.

Characteristic Entire study cohortb Vaccinated with XBB.1.5-containing vaccineb
Total vaccinated 1 076 531 902 803
Age, mean (SD), y 74.7 (7.4) 74.5 (7.1)
Sex
Female 578 655 (53.8) 485 985 (53.8)
Male 497 876 (46.2) 416 818 (46.2)
Region of residency in Denmark
Capital 287 942 (26.7) 241 272 (26.7)
Central 244 866 (22.7) 206 370 (22.9)
Northern 120 854 (11.2) 100 554 (11.1)
Zealand 176 838 (16.4) 148 797 (16.5)
Southern 246 009 (22.9) 205 800 (22.8)
Vaccination priority groups
Age priority 952 568 (88.5) 810 657 (89.8)
High risk of severe COVID-19 92 829 (8.6) 67 096 (7.4)
Health care workers 31 134 (2.9) 25 050 (2.8)
Vaccine type received as the fifth dose
XBB.1.5-containing vaccine 902 803 (83.9) 902 803 (100.0)
None 172 756 (16.0) NA
Other COVID-19 vaccine 972 (0.1) NA
Comorbidities
Chronic cardiac disorder 198 438 (18.4) 162 215 (18.0)
Malignancy 89 780 (8.3) 72 985 (8.1)
Autoimmune disorder 69 137 (6.4) 57 821 (6.4)
Diabetes 57 256 (5.3) 45 459 (5.0)
Psychiatric disorder 55 281 (5.1) 40 731 (4.5)
Chronic respiratory disorder 45 302 (4.2) 35 268 (3.9)
Asthma 20 649 (1.9) 17 822 (2.0)
Kidney disorder 17 360 (1.6) 12 771 (1.4)
Epilepsy 8940 (0.8) 7021 (0.8)

Abbreviation: NA, not applicable.

a

Cohort consisted of all individuals aged ≥65 years vaccinated with a bivalent BA.4-5 or BA.1 mRNA booster as a fourth dose overall and those individuals receiving a monovalent XBB.1.5-containing vaccine as a fifth dose in Denmark. The start of the study period was September 15, 2022, corresponding to the national rollout date of the fourth COVID-19 vaccine dose, while the monovalent XBB.1.5-containing mRNA vaccine was administered from October 1, 2023, and the study period ended on January 8, 2024.

b

Values are numbers (percentages) unless otherwise stated.