Table 1.
CU | MCI | ADD | p value | |
---|---|---|---|---|
N | 145 | 220 | 139 | - |
Age in years, mean ± SE | 67.8 ± 0.472 | 72.8 ± 0.397 | 73.8 ± 0.563 | < 2.00 × 10−16a |
Sex (M:F) | 72:73 | 106:114 | 59:80 | 0.429b |
Years of education, mean ± SE | 13.8 ± 0.230 | 13.0 ± 0.189 | 12.5 ± 0.266 | 8.69 × 10−4 a |
APOEε4 alleles (0:1:2) | 109:34:2 | 106:97:17 | 55:62:22 | 2.31 × 10−10 c |
APOEε2 alleles (0:1:2) | 134:11:0 | 211:9:0 | 133:6:0 | 0.323 c |
Abbreviations: CU Cognitively unimpaired, MCI Mild cognitive impairment, ADD Alzheimer’s disease dementia, APOE Apolipoprotein E, SE Standard error, ANOVA analysis of variance
aOne-way ANOVA
bChi-squared test
cFisher’s exact test