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. 2024 Feb 27;16:45. doi: 10.1186/s13195-024-01414-x

Table 2.

Nagelkerke's R2 at differenct p value thresholds

PRS (All SNPs) PRS.noAPOE (except APOE region)
pT Nagelkerke's R2 p value #SNPs Nagelkerke's R2 p value #SNPs
p < 5 × 10–8 0.148 5.92 × 10–8 81 0.081 4.57 × 10–5 44
p < 1 × 10–6 0.143 9.91 × 10–8 107 0.067 2.07 × 10–4 70
p < 1 × 10–5 0.167 1.40 × 10–8 173 0.085 3.18 × 10–5 131
p < 1 × 10–4 0.091 1.53 × 10–5 410 0.029 0.013 364
p < 1 × 10–3 0.034 6.85 × 10–3 1,696 0.014 0.077 1,642
p < 1 × 10–2 0.004 0.324 10,101 0.007 0.213 10,041
p < 0.05 0.000 0.929 33,065 0.000 0.979 32,999
p < 0.5 0.005 0.288 121,721 0.004 0.332 121,647
p < 1.0 0.006 0.262 158,289 0.005 0.303 158,208

The highest accuracy was highlighted in bold

P value was calculated by Wald test