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KLF participates in the pyroptosis process of ulcerative enteritis through positive regulation of TXNIP/NLRP3 pathway. Adenosine 5‐triphosphate/lipopolysaccharide stimulation can activate the expression of KLF4, and KLF4 is regulating the expression of TXNIP. At the same time, TXNIP/NLRP3 signaling pathway is the classic pathway regulating pyroptosis. Therefore, in this study, KLF4 regulates TXNIP/NLRP3 pathway to participate in the pyroptosis process of Ulcerative colitis.
