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Physicochemical characterization and mRNA loading efficiency evaluation in LNPs. a) Diameter of mRNA-containing LNPs as determined via dynamic light scattering measurements. b) Cryo-TEM imaging of eGFP mRNA LNPs. The scale bar represents 25 nm. c) Surface charge of mRNA-containing LNPs as determined by zeta potential analysis. d) Loading efficiency of mRNA within LNPs. Results represent mean ± STDEV.
