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. Author manuscript; available in PMC: 2024 Feb 27.
Published in final edited form as: Eur J Pharm Sci. 2023 Jan 13;183:106370. doi: 10.1016/j.ejps.2023.106370

Fig. 5.

Fig. 5.

In vivo evaluation of luciferase expression following LNP delivery to lungs undergoing fibrosis. a) Representative whole-body bioluminescence images of bleomycin-treated mice at different timepoints after intratracheal administration of Cy5-Luc mRNA LNPs. Upper panel: Whole-body epifluorescence images. Lower panel: Corresponding bioluminescence after intraperitoneal injection of D-luciferin. b) Average radiance of luminescence in bleomycin-treated mice at different timepoints after intratracheal administration of Cy5-Luc mRNA LNPs (N=5). Results represent mean ± STDEV.