Fig. 8. DNA computing for signal processing. a, Suggested mechanism of operation of the automaton by DNA-based state transition using the restriction nuclease FokI and ligase (right).193 b, “Seesawing”, “thresholding”, and “reporting” DNA reactions.360 c, The decision architecture (left) of the neural network. Fluorescence levels of α, β and γ, measured in approximately 25 000 droplets (right).361 d, Illustration of the AND gate operation using DNA droplets (left). CLSM images for droplet phase separation corresponding to four input patterns (right). Scale bars: 10 μm.212 Figures reproduced with permission from: a, ref. 193, copyright 2003, National Academy of Sciences; b, ref. 360, copyright 2012, Elsevier; c, ref. 361, copyright 2023, Royal Chemical Society; d, ref. 212, copyright 2022, Wiley-VCH.
