TABLE 2.
Effects of RB C-terminal fragments on terminal growth arrest
| Transfected RB plasmid(s) | Flat cellsa | Neor coloniesb |
|---|---|---|
| pCMV | − | ++ |
| pCMV-wtRB | ++ | − |
| pCMV-SE | − | ++ |
| pCMV-SEΔ | − | ++ |
| pCMV-SE-13S | − | ++ |
| pCMV-wtRB + pCMV-SE | +/− | ND |
| pCMV-wtRB + pCMV-SEΔ | +/− | ND |
| pCMV-wtRB + pCMV-SE-13S | ++ | ND |
a
Numbers of flat cells formed relative to that formed by wild-type RB (++) are schematically shown. +/− indicate a number less than 10% of that formed by wild-type RB, and − indicates a number less than 1% of that formed by wild-type RB.
b
Numbers of neomycin-resistant colonies relative to the number of pCMV-vector-transfected colonies (++; 100%) are schematically shown. − indicates a colony number less than 10% of that of the vector control. ND, not determined.