Table 2.
Baseline Demographics of the UK Biobank Participants Included in our Analysis
| Characteristics | Total (n = 49 229) | Female (n = 27366) | Male (n = 21863) | P∗ |
|---|---|---|---|---|
| Age, median (IQR) | 58 (50–63) | 57 (50–63) | 58 (50–63) | < 0.001 |
| Total cholesterol, mean ± SD, mmol/L | 5.7 ± 1.1 | 5.9 ± 1.1 | 5.6 ± 1.1 | < 0.001 |
| HDL cholesterol, mean ± SD, mmol/L | 1.5 ± 0.4 | 1.6 ± 0.4 | 1.3 ± 0.3 | < 0.001 |
| Body mass index, mean ± SD, kg/m2 | 27.2 ± 4.7 | 26.8 ± 5.1 | 27.7 ± 4.1 | < 0.001 |
| Diastolic blood pressure, mean ± SD, mm Hg | 81.7 ± 10 | 80.1 ± 9.9 | 83.6 ± 9.7 | < 0.001 |
| Systolic blood pressure, mean ± SD, mm Hg | 136.8 ± 18.3 | 134.4 ± 19 | 139.8 ± 16.9 | < 0.001 |
| HbA1c, mean ± SD, mmol/mol | 35.5 ± 6 | 35.4 ± 5.5 | 35.7 ± 6.5 | < 0.001 |
| Diabetes mellitus, n (%) | < 0.001 | |||
| No | 47033 (95.5) | 26479 (96.8) | 20 554 (94) | |
| Yes | 2196 (4.5) | 887 (3.2) | 1309 (6) | |
| Current smoker, n (%) | < 0.001 | |||
| No | 44 527 (90.7) | 25 205 (92.4) | 19 333 (88.7) | |
| Yes | 4545 (9.3) | 2079 (7.6) | 2466 (11.3) |
HbA1c = glycosylated hemoglobin; HDL = high density lipoprotein; IQR = interquartile range; SD = standard deviation.
∗
P value for parametric 1-way analysis of variance test or the nonparametric Kruskal‒Wallis test.