Table 2.
Insulin resistance indicators in all groups
| C group (n = 45) | P1 group (n = 42) | P2 group (n = 42) | p | |
|---|---|---|---|---|
| FPG (mmol/L, mean ± SD) | ||||
| T1 | 5.09 ± 0.63 | 5.04 ± 0.55 | 4.96 ± 0.69 | 0.591 |
| T2 | 4.73 ± 0.64 | 5.12 ± 0.80 | 5.26 ± 1.02a | 0.011 |
| T3 | 5.21 ± 0.80 | 5.30 ± 0.81 | 5.21 ± 0.85 | 0.847 |
| FINS (mU/L, mean ± SD) | ||||
| T1 | 39.50 ± 8.54 | 35.89 ± 9.57 | 37.25 ± 9.44 | 0.181 |
| T2 | 44.01 ± 9.74 | 44.51 ± 8.50 | 44.80 ± 8.96 | 0.920 |
| T3 | 33.50 ± 7.38 | 30.48 ± 7.18 | 32.92 ± 7.47 | 0.134 |
| Glucagon (pg/mL, mean ± SD) | ||||
| T1 | 376.41 ± 86.07 | 379.76 ± 70.86 | 396.32 ± 76.11 | 0.453 |
| T2 | 327.88 ± 102.03 | 300.27 ± 100.36 | 305.49 ± 96.05 | 0.389 |
| T3 | 352.58 ± 114.47 | 324.07 ± 121.49 | 362.78 ± 103.25 | 0.271 |
| HOMA-IR (mean ± SD) | ||||
| T1 | 8.97 ± 2.37 | 8.13 ± 2.62 | 8.18 ± 2.25 | 0.189 |
| T2 | 9.29 ± 2.52 | 10.12 ± 2.44 | 10.38 ± 2.63 | 0.113 |
| T3 | 7.78 ± 2.23 | 7.23 ± 2.22 | 7.62 ± 2.14 | 0.489 |
| HOMA-β (median (interquartile range)) | ||||
| T1 | 534.65 (361.18) | 472.37 (159.49) | 526.12 (390.59) | 0.266 |
| T2 | 639.37 (632.64) | 590.45 (612.96) | 519.74 (682.87) | 0.403 |
| T3 | 389.63 (312.96) | 344.07 (257.34) | 380.43 (208.78) | 0.531 |
| HOMA-IS (median (interquartile range)) | ||||
| T1 | 0.28 (0.01) | 0.28 (0.02) | 0.28 (0.02) | 0.246 |
| T2 | 0.28 (0.01) | 0.28 (0.01) | 0.28 (0.01) | 0.218 |
| T3 | 0.29 (0.02) | 0.29 (0.02) | 0.29 (0.01) | 0.421 |
Values are mean ± standard deviation or median (interquartile range). p: overall comparison
T1 preoperative day 1, T2 10 min before intubation, T3 1 hour after surgery, FPG fasting plasma glucose, FINS fasting insulin, HOMA-IR homeostasis model assessment-insulin resistance index, HOMA-β homeostasis model assessment-β, HOMA-IS homeostasis model assessment-insulin sensitivity index, SD standard deviation
aCompared with the C group, p < 0.05