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. 2024 Feb 14;15:1356321. doi: 10.3389/fimmu.2024.1356321

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Copyright © 2024 Pellegrino, Secli, D’Amico, Petrilli, Caforio, Folgiero, Tumino, Vacca, Vinci, Fruci and de Billy

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Effect of IGF1/IGF1R pathway activation on the immune cell populations of the TME. Activation of the IGF1/IGF1R axis affects differently the indicated immune cell subtypes promoting immunosuppression and cancer progression.