Table 1.
Demographic and clinical characteristics of the study population.
| Parameter | Total | HIE | no HIE | p-value* |
|---|---|---|---|---|
| n | 168 | 88 | 80 | |
| Age | 60 [48–70] | 57 [44–68] | 63 [54–72] | 0.021 |
| Sex | ||||
| Male | 118 (70.2%) | 60 (68.2%) | 58 (72.5%) | 0.271 |
| OHCA | 128 (76.2%) | 73 (83.0%) | 55 (68.8%) | 0.033 |
| Shockable Rhythm (n = 167/88/79) | 78 (46.7%) | 37 (42.0%) | 41 (51.9%) | 0.205 |
| Primary cause of arrest (n = 166/87/79) | 0.075 | |||
| Cardiac | 69 (41.6%) | 29 (33.3%) | 40 (50.6%) | |
| Respiratory | 39 (23.5%) | 24 (27.6%) | 15 (19.0%) | |
| Other ** | 58 (34.9%) | 34 (39.1%) | 24 (30.4%) | |
| Time to ROSC (min) (n = 157/81/76) | 20 [10–30] | 22 [15–60] | 12 [8–21] | 0.007 |
| Total Adrenalin Dose (mg) (n = 157/87/70) | 2 [1–5] | 4 [2–7] | 2 [1–3] | <0.001 |
| APACHE Score (n = 165/86/79) | 36 [30–40] | 37 [31–41] | 34 [29–39] | 0.1 |
| Length of ICU stay (days) | 10 [5–17] | 5 [3–11] | 15 [10–28] | <0.001 |
| Time on Ventilator (hours) | 170 [96–334] | 123 [60–235] | 242 [135–432] | 0.003 |
| CT acquisition (hours after CA) (n = 167/88/79) | 20 [3–93] | 18 [3–85] | 34 [4–125] | 0.004 |
| Neurological outcome at hospital discharge | <0.001 | |||
| CPC 1 | 36 | 0 | 36 | |
| CPC 2 | 22 | 0 | 22 | |
| CPC 3 | 4 | 1 | 3 | |
| CPC 4 | 11 | 9 | 2 | |
| CPC 5 | 95 | 78 | 17 |
*Mann–Whitney U test (resp. Welch’s t-tests). **Intoxication, metabolic and unknown cases.