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. 2023 Aug 24;47(1):97–112. doi: 10.1007/s13402-023-00853-2

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Immune landscape of HSC-Prog cells in AML and healthy samples. a Heatmap of 50 hallmark gene sets in the MSigDB database among the healthy and AML. b Heatmap of AUCell tvalue of transcription factor in HSC-Prog cells among AML patients and healthy donors. Red and blue represent upregulated and downregulated TFs, respectively. c Heatmap showing the total number of interactions between cell types in the decidua dataset obtained from CellPhoneDB. Red and blue represent a high and low number of interactions, respectively. d Connectome web analysis of lean interacting tissue-resident cell types based on the expression in the cell population. The thickness of the connecting lines is proportional to the number of interactions between two nodes. e Dot plot depicting selected cell–cell interactions between HSC-Prog and other clusters. The size of the dots represents the statistical significance of the interaction. Red and blue represent high and low marker expression levels, respectively