Table 3.
Clinical parameters | N (%) | TMT-A Z score | TMT-B Z score | DB Z score | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Baseline | Change | 95% CI | p-value | Baseline | Change | 95% CI | p-value | Baseline | Change | 95% CI | p-value | ||
All patients | 46 (100) | −1.42 | 0.024 | 0.006–0.042 | 0.009 | −2.01 | 0.034 | 0.012–0.057 | 0.003 | −0.53 | 0.019 | 0.011–0.028 | <0.001 |
Psychiatric comorbidity | |||||||||||||
No | 34 (73.9) | −0.99 | 0.018 | −0.01–0.040 | 0.13 | −1.55 | 0.025 | 0.004–0.047 | 0.018 | −0.34 | 0.017 | 0.007–0.026 | 0.001 |
Yes | 12 (26.1) | −2.61 | 0.042 | 0.014–0.07 | 0.003 | −3.58 | 0.058 | 0.004–0.113 | 0.036 | −1.13 | 0.028 | 0.009–0.046 | 0.003 |
Epilepsy type | |||||||||||||
FLE | 18 (39.1) | −1.57 | 0.030 | −0.01–0.07 | 0.142 | −2.38 | 0.032 | −0.014–0.079 | 0.172 | −0.80 | 0.013 | 0.0–0.026 | 0.055* |
TLE | 17 (37) | −1.79 | 0.024 | 0.002–0.044 | 0.028 | −2.37 | 0.040 | 0.006–0.074 | 0.020 | −0.74 | 0.012 | −0.003–0.026 | 0.120 |
Other | 11 (23.9) | −0.89 | −0.009 | −0.084–0.065 | 0.810 | −1.13 | 0.008 | −0.036–0.053 | 0.717 | 0.18 | 0.003 | −0.018–0.023 | 0.795 |
Predominant seizure type | |||||||||||||
FAS/FIAS | 34 (73.9) | −1.17 | 0.019 | −0.005–0.043 | 0.123 | −1.74 | 0.034 | 0.009–0.058 | 0.006 | −0.45 | 0.018 | 0.008–0.029 | 0.001 |
FBTCS | 12 (26.1) | −2.37 | 0.035 | 0.009–0.061 | 0.008 | −3.12 | 0.025 | −0.029–0079 | 0.37 | −0.73 | 0.018 | 0.004–0.033 | 0.013 |
ASMs | |||||||||||||
1–2 | 17 (37) | −0.90 | 0.042 | 0.015–0.068 | 0.002 | −0.98 | 0.042 | 0.014–0.071 | 0.004 | −0.10 | 0.014 | −0.003–0.031 | 0.114 |
3–4 | 29 (63) | −1.77 | 0.012 | −0.011–0.035 | 0.312 | −2.76 | 0.030 | −0.001–0.060 | 0.058 | −0.80 | 0.023 | 0.013–0.033 | <0.001 |
ASM, antiseizure medication; FAS, focal aware seizure; FBTCS, focal to tonic clonic seizure; FIAS, focal impaired awareness seizure; FLE, frontal lobe epilepsy; TLE, temporal lobe epilepsy. Bold values indicate statistically significant p-values.