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. 2024 Feb 14;15:1349201. doi: 10.3389/fpsyt.2024.1349201

Table 3.

Baseline values and changes in z-scores per month for overall patients as well as in different clinical categories.

Clinical parameters N (%) TMT-A Z score TMT-B Z score DB Z score
Baseline Change 95% CI p-value Baseline Change 95% CI p-value Baseline Change 95% CI p-value
All patients 46 (100) −1.42 0.024 0.006–0.042 0.009 −2.01 0.034 0.012–0.057 0.003 −0.53 0.019 0.011–0.028 <0.001
Psychiatric comorbidity
No 34 (73.9) −0.99 0.018 −0.01–0.040 0.13 −1.55 0.025 0.004–0.047 0.018 −0.34 0.017 0.007–0.026 0.001
Yes 12 (26.1) −2.61 0.042 0.014–0.07 0.003 −3.58 0.058 0.004–0.113 0.036 −1.13 0.028 0.009–0.046 0.003
Epilepsy type
FLE 18 (39.1) −1.57 0.030 −0.01–0.07 0.142 −2.38 0.032 −0.014–0.079 0.172 −0.80 0.013 0.0–0.026 0.055*
TLE 17 (37) −1.79 0.024 0.002–0.044 0.028 −2.37 0.040 0.006–0.074 0.020 −0.74 0.012 −0.003–0.026 0.120
Other 11 (23.9) −0.89 −0.009 −0.084–0.065 0.810 −1.13 0.008 −0.036–0.053 0.717 0.18 0.003 −0.018–0.023 0.795
Predominant seizure type
FAS/FIAS 34 (73.9) −1.17 0.019 −0.005–0.043 0.123 −1.74 0.034 0.009–0.058 0.006 −0.45 0.018 0.008–0.029 0.001
FBTCS 12 (26.1) −2.37 0.035 0.009–0.061 0.008 −3.12 0.025 −0.029–0079 0.37 −0.73 0.018 0.004–0.033 0.013
ASMs
1–2 17 (37) −0.90 0.042 0.015–0.068 0.002 −0.98 0.042 0.014–0.071 0.004 −0.10 0.014 −0.003–0.031 0.114
3–4 29 (63) −1.77 0.012 −0.011–0.035 0.312 −2.76 0.030 −0.001–0.060 0.058 −0.80 0.023 0.013–0.033 <0.001

ASM, antiseizure medication; FAS, focal aware seizure; FBTCS, focal to tonic clonic seizure; FIAS, focal impaired awareness seizure; FLE, frontal lobe epilepsy; TLE, temporal lobe epilepsy. Bold values indicate statistically significant p-values.