Table 6.
Randomized controlled trials comparing different doses of dexamethasone.
| Reference (authors, year) | Extubation | Reintubation | BPD | Others respiratory outcome | Systemic hypertension | HG | Sepsis/infection | PDA | IVH | NEC | ROP | Long-term NDV | Long-term growth |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Marr (47) | + | + | = | = | = | = | = | ND | = | = | = | 7 years + | 7 years: = |
| Odd (48) | = | ND | NE | = | = | = | = | NE | = | NE | NE | 9 and 18 months of postnatal age = | NE |
| Malloy (49) | = | ND | = | = | − | = | NE | NE | = | = | = | At 1 years − | NE |
| McEvoy (50) | NE | NE | = | + | = | = | = | NE | = | = | = | At 1 years = | NE |
| Durand (51) | NE | NE | = | + | = | = | = | NE | = | = | = | NE | NE |
| Armstrong (52) | ND | ND | + | = | = | NE | NE | NE | = | NE | NE | 18 months of = | 18 months of = |
| Merz (53) | + | ND | = | + | = | = | = | NE | NE | = | = | NE | NE |
| Bloomfield (54) | NE | NE | + | + | = | = | = | NE | NE | = | = | NE | NE |
+, Better outcome for intervention group (steroids administration); −, Worse outcome for intervention group (steroids administration); =, no differences between intervention and control groups; NE, not evaluated; ND, not declared; BPD, bronchopulmonary dysplasia; HG, hyperglycemia; PDA, patent ductus arteriosus; IVH, intraventricular hemorrhage; NEC, necrotizing enterocolitis; ROP, retinopathy of prematurity; NDV, neurodevelopment; GA, gestational age; BW, birth weight.