Table 1.
Clinical characteristics of patients with AF with and without moderate-to-severe OSA.
| All patients (n = 320) |
Mild or no OSA (n = 149) |
Moderate-to-severe OSA (n = 171) |
p-value | ||
|---|---|---|---|---|---|
| Male, n (%) | 231 (72.2%) | 94 (63.1%) | 137 (80.1%) | <0.001 | |
| Age, years | 62.0 ± 0.6 | 59.1 ± 0.9 | 64.5 ± 0.8 | <0.001 | |
| BMI, kg/m2 | 25.6 ± 0.2 | 24.6 ± 0.2 | 26.4 ± 0.3 | <0.001 | |
| Hypertension, n (%) | 117 (36.6%) | 43 (28.9%) | 74 (43.3%) | 0.008 | |
| Diabetes mellitus, n (%) | 49 (15.3%) | 13 (8.7%) | 36 (21.1%) | 0.002 | |
| Heart failure, n (%) | 17 (5.3%) | 3 (2.0%) | 14 (8.2%) | 0.014 | |
| Stroke, n (%) | 17 (5.3%) | 5 (3.4%) | 12 (7.0%) | 0.145 | |
| Coronary artery disease, n (%) | 37 (11.6%) | 12 (8.1%) | 25 (14.6%) | 0.067 | |
| Paroxysmal AF, n (%) | 224 (70.0%) | 116 (77.9%) | 108 (63.2%) | 0.004 | |
| Ablation, n (%) | 58 (18.1%) | 27 (18.1%) | 31 (18.1%) | 0.999 | |
| AF burden (%) | 38.7 ± 2.5 | 31.4 ± 3.4 | 45.1 ± 3.5 | 0.005 | |
| ESS | 7.2 ± 0.2 | 6.9 ± 0.3 | 7.4 ± 0.3 | 0.181 | |
| Left atrial diameter (cm) | 4.1 ± 0.0 | 4.0 ± 0.1 | 4.3 ± 0.1 | 0.001 | |
| LVEF (%) | 69.6 ± 0.5 | 70.0 ± 0.7 | 69.3 ± 0.7 | 0.431 | |
| AHI, event/h | 18.9 ± 0.8 | 7.0 ± 0.4 | 29.4 ± 0.9 | <0.001 |
AF, atrial fibrillation; AHI, apnea-hypopnea index; BMI, body mass index; ESS, Epworth Sleepiness Scale; LVEF, left ventricular ejection fraction; and OSA, obstructive sleep apnea.