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. 2024 Jan 23;52(4):1628–1644. doi: 10.1093/nar/gkae017

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© The Author(s) 2024. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Association of CMC and non-CMC target genes with different functional categories. (A–E) Bubble plots illustrating FE of CMC (blue bubbles) and non-CMC (pink bubbles) target genes in gene categories defined by Gene Ontology BP terms (A), DisGeNET-associated diseases (B), Reactome pathways (C), KEGG pathways (D) and MSigDB hallmarks (E). Bubble sizes are proportional to –log₁₀(q-values) (see legend). Each plot shows 20 representative categories associated with CMC miRNA gene targets with the lowest q-values. Full lists of associated categories are shown in Supplementary Table S8. Asterisk indicates terms with shortened names presented on the plot; for underlined terms no enrichment was indicated in non-CMC.