Figure 4.

Changes in glycemic control in 26 outpatients with type 2 diabetes and end-stage renal disease requiring dialysis who switched from SC insulin therapy to a fully closed-loop automated insulin delivery system. Before vs after metrics were: TIR, (100-180 mg/dL) 38% vs 53%; time in hyperglycemia 57% vs 43%; mean glucose, 209 mg/dL vs 182 mg/dL; and time in hypoglycemia, 0.2% vs 0.1%. Subjects using AIDs achieved 3.5 additional hours each day with glucose in target range.

Source: Figure reproduced from Boughton et al. ⁴ under the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0, https://creativecommons.org/licenses/by/4.0/). Abbreviations: ESRD, end-stage renal disease; SC, subcutaneous; TIR, time-in-range.