Table 2. Characteristics of EHOF according to the etiology and infection.
| Etiology |
Bacterial infection |
|||||
|---|---|---|---|---|---|---|
| HBV, n=427 | Alcohol, n=145 | p-value | No, n=382 | Yes, n=354 | p-value | |
| Brain, n (%) | 21 (4.9) | 7 (4.8) | 1.000 | 18 (4.7) | 18 (5.1) | 0.865 |
| Renal, n (%) | 47 (11.0) | 32 (22.1) | 0.001 | 30 (7.9) | 66 (18.6) | <0.001 |
| Coagulation, n (%) | 209 (48.9) | 64 (44.1) | 0.337 | 161 (42.1) | 185 (52.3) | 0.006 |
| Respiratory, n (%) | 20 (4.7) | 9 (6.2) | 0.511 | 16 (4.2) | 16 (4.5) | 0.858 |
| Circulatory, n (%) | 11 (2.6) | 5 (3.4) | 0.566 | 5 (1.3) | 12 (3.4) | 0.084 |
| Number of EHOF, n (%) | 0.514 | <0.001 | ||||
| None | 194 (45.4) | 63 (43.4) | 197 (51.6) | 137 (38.7) | ||
| SEHOF | 168 (39.3) | 54 (37.2) | 144 (37.7) | 151 (42.7) | ||
| MEHOF | 65 (15.2) | 28 (19.3) | 41 (10.7) | 66 (18.6) | ||
| Onset time of EHOF, n (%) | n=233 | n=82 | 0.585 | n=185 | n=217 | 0.286 |
| Early onset | 159 (68.2) | 53 (64.6) | 130 (70.3) | 141 (65.0) | ||
| Late onset | 74 (31.8) | 29 (35.4) | 55 (29.7) | 76 (35.0) | ||
| Sequence of EHOF in MEHOF, n (%) | n=65 | n=28 | 0.575 | n=41 | n=66 | 0.006 |
| Brain first | 4 (6.2) | 2 (7.1) | 4 (9.8) | 2 (3.0) | ||
| Renal first | 6 (9.2) | 4 (14.3) | 0 (0.0) | 11 (16.7) | ||
| Coagulation first | 34 (52.3) | 10 (35.7) | 20 (48.8) | 29 (43.9) | ||
| Respiratory or circulatory first | 3 (4.6) | 3 (10.7) | 0 (0.0) | 6 (9.1) | ||
| Two or more organs simultaneously | 18 (27.7) | 9 (32.1) | 17 (41.5) | 18 (27.3) | ||
EHOF, extra-hepatic organ failure; HBV, hepatitis B virus; MEHOF, multiple extra-hepatic organs failure; SEHOF, single extra-hepatic organ failure.