Table 3. Survival of ACLF patients based on the characteristics of EHOF.
| Subgroup | 28-day survival (%) | 90-day survival (%) | OR (95% CI) | p-value |
|---|---|---|---|---|
| By existence of EHOF | <0.001 | |||
| No | 89.9 | 79.6 | Ref | |
| Yes | 68.6 | 52.3 | 2.95 (2.28–3.82) | |
| By number of EHOF | <0.001 | |||
| SEHOF | 76.2 | 60.0 | Ref | |
| MEHOF | 48.2 | 30.6 | 2.47 (1.87–3.26) | |
| By onset of EHOF | 0.910 | |||
| Early onset | 65.7 | 53.2 | Ref | |
| Late onset | 74.7 | 51.1 | 1.02 (0.77–1.34) | |
| By organ type in SEHOF | ||||
| Brain | 50.0 | 33.3 | Ref | |
| Renal | 65.7 | 50.4 | 0.47 (0.18–1.25) | 0.131 |
| Coagulation | 77.5 | 61.2 | 0.32 (0.13–0.78) | 0.012 |
| Respiratory or circulatory | 91.7 | 75.0 | 0.15 (0.04–0.57) | 0.005 |
| By organ sequence in MEHOF | ||||
| Brain first | 33.3 | 0.0 | Ref | |
| Renal first | 72.7 | 31.2 | 0.52 (0.17–1.56) | 0.241 |
| Coagulation first | 42.3 | 25.9 | 0.66 (0.26–1.70) | 0.392 |
| Respiratory or circulatory first | 66.7 | 44.4 | 0.45 (0.12–1.69) | 0.236 |
| Two or more organs simultaneously | 47.9 | 42.6 | 0.58 (0.22–1.53) | 0.267 |
ACLF, acute-on-chronic liver failure; EHOF, extra-hepatic organ failure; MEHOF, multiple extra-hepatic organs failure; SEHOF, single extra-hepatic organ failure.