Table 1. Patient Demographics, Clinical Characteristics, and TSP of the Patients Diagnosed with Ovarian Carcinoma in The Cancer Genome Atlas Cohort.
| Characteristic | Patients, No. (%)a | P valueb | ||
|---|---|---|---|---|
| All (N = 103) | TSP = 0 (n = 85) | TSP = 1 (n = 18) | ||
| Age at diagnosis, mean (SD), y | 61.6 (11.1) | 61.4 (11.2) | 62.7 (11.1) | .66 |
| International Federation of Gynecology and Obstetrics stage | .91 | |||
| Stage IC | 2 (1.9) | 2 (2.3) | 0 | |
| Stage IIA | 1 (1.0) | 1 (1.2) | 0 | |
| Stage IIB | 1 (1.0) | 1 (1.2) | 0 | |
| Stage IIC | 2 (1.9) | 1 (1.2) | 1 (5.6) | |
| Stage IIIB | 1 (1.0) | 1 (1.2) | 0 | |
| Stage IIIC | 72 (69.9) | 59 (69.4) | 13 (72.2) | |
| Stage IV | 23 (22.3) | 19 (22.3) | 4 (22.2) | |
| Unknown | 1 (1.0) | 1 (1.0) | 0 | |
| Residual disease | .76 | |||
| No | 21 (20.4) | 18 (21.1) | 3 (16.6) | |
| Yes | 76 (73.8) | 63 (74.1) | 13 (72.2) | |
| Unknown | 6 (5.8) | 4 (4.7) | 2 (11.1) | |
| Chemoresistance | .78 | |||
| No | 60 (58.2) | 49 (57.6) | 12 (66.7) | |
| Yes | 12 (11.7) | 12 (14.1) | 2 (11.1) | |
| Unknown | 31 (30.1) | 24 (28.2) | 4 (22.2) | |
Abbreviation: TSP, tumor-stroma proportion.
a
Cases with low TSP (<50%) are labeled as TSP = 0 and cases with high TSP (≥50%) are labeled as TSP = 1.
b
Comparisons of categorical variables were conducted using Pearson χ2 tests, and the comparison of age between the groups was conducted using a t test with pooled variance.