Table 1.
Hypotheses tested and corresponding analyses. This table provides a comprehensive overview of the analyses, brain areas, atlas employed, and statistical methods used for each hypothesis tested in this study.
| Hypotheses tested | Analyses | Considered brain areas | Atlas | Statistical analysis |
|---|---|---|---|---|
| Hypothesis 1 | Activation analysis (ROI-based) | All 7 sub-thalamic regions (L/R) | Oxford thalamic connectivity atlas | Small volume correction |
| Hypothesis 2 | Activation analysis (ROI-based) | Primary auditory cortex (L/R): Heschl’s gyrus | Harvard-Oxford cortical and subcortical structural atlases | Small volume correction |
| Hypothesis 3 | Activation analysis (ROI-based) | Secondary regions (L/R): superior temporal gyrus (both anterior and posterior division) | Harvard-Oxford cortical and subcortical structural atlases | Small volume correction |
| Hypothesis 4 | ROI-to-ROI based connectivity | 2 sub-thalamic (sensory and temporal) nuclei and Heschl’s gyrus | Oxford thalamic connectivity atlas/ Harvard-Oxford cortical and subcortical structural atlases | Subject-level: wGLM Group-level: LME |
| Hypothesis 5 | ROI-to-ROI based connectivity | Heschl’s gyrus and superior temporal gyrus (both anterior and posterior division) | Harvard-Oxford cortical and subcortical structural atlases | Subject-level: wGLM Group-level: LME |
| Hypothesis 6 | Voxel-to-voxel connectivity | Whole cortical and subcortical brain matters | No atlas | Subject-level: Intrinsic connective analysis Group-level: LME |
| Hypothesis 7 | Spectrogram analysis | All 7 sub-thalamic regions (L/R); Primary auditory cortex (L/R): Heschl’s gyrus; Secondary regions (L/R): superior temporal gyrus (both anterior and posterior division) | Oxford thalamic connectivity atlas; Harvard-Oxford cortical and subcortical structural atlases; Harvard-Oxford cortical and subcortical structural atlases | Subject-level: Short Time Fourier Transform (STFT) for regional spectrogram estimation. Group-level: LME |