Table 5. Multifactorial analysis of demographic and clinical characteristics in relation to CB2R cytoplasmic distribution, membranous distribution, and immunohistochemical score.

OR, odds ratio; CI, confidence interval; CB2R, cannabinoid type 2 receptor

	Reference category	CB2R cytoplasmic distribution				CB2R membranous				CB2R immunohistochemical  score
		OR	95% CI		P-value	OR	95% CI		P-value	OR	95% CI		P-value
Age	-	0.97	0.92	103	0.367	1.01	0.96	1.05	0.821	1.03	0.99	1.07	0.190
Gender  (male)	Female	3.59	0.86	15.00	0.080	1.89	0.54	6.55	0.317	2.56	0.83	7.89	0.103
Grade					0.093				0.621				0.639
2	1	0.66	0.10	4.40	0.669	0.65	0.08	4.99	0.678	0.61	0.16	2.26	0.456
3		5.01	0.46	54.94	0.187	0.40	0.05	3.33	0.397	0.94	0.22	3.98	0.928
Stage Τα					0.946				0.539				0.947
2	1	1.38	0.11	16.84	0.802	0.55	0.10	3.00	0.487	1.02	0.24	4.33	0.974
3		0.83	0.11	6.18	0.855	0.45	0.10	2.14	0.313	0.80	0.19	3.29	0.752
Histologic type					0.374				<0.0005				0.053
Papillary	Clear cell	3.83	0.39	37.48	0.249	0.03	0.0	0.16	<0.0005	1.12	0.35	3.57	0.854
Chromophobe		3.03	0.27	33.74	0.368	0.65	0.14	3.08	0.588	5.90	1.15	30.23	0.033