Table 2: Estimated unadjusted associations with response at sweep 8 (age 50), consent to health record linkage and Hospital Episode Statistics (HES) linkage among cohort members eligible for HES linkage (lived in England at one or more waves between wave 6 and wave 9) and in the wave 8 target population (still alive and living in UK at age 50) (n = 10,355).
| Sequential 1 | ||||||||||
| Response at wave 8 (age 50) | Consent to linkage | Linked HES data | ||||||||
| N (%) | n (%) | RR | 95% CI | n (%) | RR | 95% CI | n (%) | RR | 95% CI | |
| Sex (N = 10,355) | ||||||||||
| Male | 5,137 (49.6) | 4,136 (80.5) | 1.00 | (ref) | 3,270 (79.1) | 1.00 | (ref) | 2,990 (91.4) | 1.00 | (ref) |
| Female | 5,218 (50.4) | 4,267 (81.8) | 1.02 | 1.00, 1.03 | 3,323 (77.9) | 0.99 | 0.96, 1.01 | 3,129 (94.2) | 1.03 | 1.02, 1.04 |
| Social class of father (N = 9,276) | ||||||||||
| I/II | 1,739 (18.8) | 1,485 (85.4) | 1.08 | 1.05, 1.11 | 1,164 (78.4) | 1.00 | 0.96, 1.04 | 1,058 (90.9) | 0.96 | 0.94, 0.99 |
| III non-manual | 964 (10.4) | 799 (82.9) | 1.05 | 1.01, 1.09 | 648 (81.1) | 1.04 | 0.99, 1.08 | 595 (91.8) | 0.97 | 0.95, 1.00 |
| III manual | 4,711 (50.8) | 3,789 (80.4) | 1.02 | 0.99, 1.04 | 2,967 (78.3) | 1.00 | 0.97, 1.03 | 2,783 (93.8) | 1.00 | 0.98, 1.01 |
| IV/V | 1,862 (20.1) | 1,475 (79.2) | 1.00 | (ref) | 1,155 (78.3) | 1.00 | (ref) | 1,088 (94.2) | 1.00 | (ref) |
| Number of persons per room (N = 9,486) | ||||||||||
| ≤1 | 6,894 (72.7) | 5,698 (82.7) | 1.10 | 1.06, 1.14 | 4,464 (78.3) | 1.02 | 0.98, 1.06 | 4,129 (92.5) | 0.97 | 0.95, 0.99 |
| >1 to 1.5 | 1,554 (16.4) | 1,230 (79.2) | 1.06 | 1.01, 1.10 | 999 (81.2) | 1.06 | 1.01, 1.11 | 937 (93.8) | 0.98 | 0.96, 1.01 |
| >1.5 | 1,038 (10.9) | 778 (75.0) | 1.00 | (ref) | 598 (76.9) | 1.00 | (ref) | 570 (95.3) | 1.00 | (ref) |
| Overall 2 | ||||||||||
| Response at wave 8 (age 50) | Consent to linkage | Linked HES data | ||||||||
| N (%) | n (%) | RR | 95% CI | n (%) | RR | 95% CI | n (%) | RR | 95% CI | |
| Sex (N = 10,355) | ||||||||||
| Male | 5,137 (49.6) | 4,136 (80.5) | 1.00 | (ref) | 3,270 (63.7) | 1.00 | (ref) | 2,990 (58.2) | 1.00 | (ref) |
| Female | 5,218 (50.4) | 4,267 (81.8) | 1.02 | 1.00, 1.03 | 3,323 (63.7) | 1.00 | 0.97, 1.03 | 3,129 (60.0) | 1.03 | 1.00, 1.06 |
| Social class of father (N = 9,276) | ||||||||||
| I/II | 1,739 (18.8) | 1,485 (85.4) | 1.08 | 1.05, 1.11 | 1,164 (66.9) | 1.08 | 1.03, 1.13 | 1,058 (60.8) | 1.04 | 0.99, 1.10 |
| III non-manual | 964 (10.4) | 799 (82.9) | 1.05 | 1.01, 1.09 | 648 (67.2) | 1.08 | 1.02, 1.15 | 595 (61.7) | 1.06 | 0.99, 1.12 |
| III manual | 4,711 (50.8) | 3,789 (80.4) | 1.02 | 0.99, 1.04 | 2,967 (63.0) | 1.02 | 0.97, 1.06 | 2,783 (59.1) | 1.02 | 0.97, 1.06 |
| IV/V | 1,862 (20.1) | 1,475 (79.2) | 1.00 | (ref) | 1,155 (62.0) | 1.00 | (ref) | 1,088 (58.4) | 1.00 | (ref) |
| Number of persons per room (N = 9,486) | ||||||||||
| ≤1 | 6,894 (72.7) | 5,698 (82.7) | 1.10 | 1.06, 1.14 | 4,464 (64.8) | 1.12 | 1.06, 1.19 | 4,129 (59.9) | 1.09 | 1.03, 1.16 |
| >1 to 1.5 | 1,554 (16.4) | 1,230 (79.2) | 1.06 | 1.01, 1.10 | 999 (64.3) | 1.12 | 1.05, 1.19 | 937 (60.3) | 1.10 | 1.03, 1.18 |
| >1.5 | 1,038 (10.9) | 778 (75.0) | 1.00 | (ref) | 598 (57.6) | 1.00 | (ref) | 570 (54.9) | 1.00 | (ref) |
RR: Risk ratio.
Risk ratios estimated using modified Poisson regression [41].
1In sequential analyses, associations are considered conditional on the outcome at the previous stage, i.e. i) response at sweep 8 among cohort members eligible for HES linkage (lived in England at one or more waves between wave 6 and wave 9) and in the sweep 8 target population (still alive and living in UK at age 50), ii) consent to health record linkage among respondents at sweep 8, and iii) successful HES linkage among cohort members who had consented.
2In overall analyses, each association is considered among all cohort members eligible for HES linkage and in the wave 8 target population.