Table 3.
Association Between Total Sleep Time and T Lymphocyte Subsets in Virally Suppressed Men Living With HIV
| CD4+ count (cells/mm3) |
CD8+ count (cells/mm3) |
CD4+/CD8+ ratio | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Total sleep time (per hour decrease) |
β | 95% CI | P-value | β | 95% CI | P-value | β | 95% CI | P-value |
| Unadjusted model | 6.2 | (−19.6, 31.9) | 0.64 | 38.9 | (6.3, 71.6) | 0.02 | −5.2% | (−9.0, −1.2%) | 0.01 |
| Adjusted model* | 1.2 | (−24.0, 26.3) | 0.93 | 31.1 | (0.8. 67.5) | 0.05 | −5.6% | (−9.4, −1.6%) | 0.007 |
Results of linear regression modeling T lymphocyte populations and the log-transformed CD4+/CD8+ T lymphocyte ratio by total sleep time on home polysomnography (N = 289). The values reported are the effects for each additional hour decrease in total sleep time.
*Adjusted for age, race, body mass index, depressive symptoms, antidepressant use, and non-nucleoside reverse transcriptase inhibitor use (N = 288).