Table 3.
Gamma Irradiation.
| Mrad | PFU/mL | Inactivated (Y/N) |
|---|---|---|
|
| ||
| 1 | 1 × 105 | N |
| 1 × 106 | N | |
| 1 × 107 | N | |
| 2 | 1 × 105 | N |
| 1 × 106 | N | |
| 1 × 107 | N | |
| 3 | 1 × 105 | Y |
| 1 × 106 | Y | |
| 1 × 107 | N | |
| 4 | 1 × 105 | Y |
| 1 × 106 | Y | |
| 1 × 107 | N | |
| 5 | 1 × 105 | Y |
| 1 × 106 | Y | |
| 1 × 107 | Y | |
| 6 | 1 × 105 | Y |
| 1 × 106 | Y | |
| 1 × 107 | Y | |
Inactivation of ZIKV by gamma irradiation of three virus titers: 1 × 105 PFU/mL, 1 × 106 PFU/mL and 1 × 107 PFU/mL was screened at gamma irradiation doses between 1 Mrad and 6 Mrad. Y: inactivation was successful (no CPE and no plaques); N: inactivation failed (positive for CPE or plaque formation).