Fig. 3. Bioinformatic analysis of the ltb BGC. (a) Representative homologous BGCs found in other fungi using cblaster with high conservation (≥48% identity across all genes). (b) BGCs homologous to the ltb BGC detected in other fungi aligned using clinker. (c) The domain architectures of the cAT domain-containing fungal HR-PKS, LtbA in A. luteorubrus, Tv6-931 in T. virens and PKS17a in M. anisopliae; KS, ketosynthase; AT, malonyl-CoA acyl transferase; DH, dehydratase; MT, methyltransferase; KR, ketoreductase; ACP, acyl carrier protein; cAT, carnitine O-acyltransferase.
