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. 2024 Feb 27;8(1):010902. doi: 10.1063/5.0190840

TABLE I.

The complex interplay between the heart and kidneys, highlighting their primary functions, contributions to homeostasis, and the potential effects on the other organ in the case of dysfunction.

Organ Primary function Contribution to homeostasis Effect on other in dysfunction
Heart Central pump of the circulatory system25–30 Regulates blood pressure Reduced blood flow to the kidneys can lead to decreased kidney function
Distributes oxygen and nutrients Potentially triggers kidney disorders due to reduced filtration
Kidneys Filtration and excretion system for waste products31–35 Regulates fluid balance High blood pressure can strain the heart and lead to heart diseases
Maintains electrolyte balance36,37 Filters waste from the bloodstream Fluid overload may exacerbate heart failure