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. 2024 Feb 9;18:e20230053. doi: 10.1590/1980-5764-DN-2023-0053

Table 3. Cognitive and neuropsychiatric data (baseline and after 6 months).

Cognitive intervention
  • Mean (SD)

  • baseline

  • Mean (SD)

  • after 6 months

p-value
Yes (n=19)
MoCA
Global score 22.1 (6.0) 23.3 (5.3) 0.022*
<26 18.7 (5.0) 21.4 (5.2) 0.019*
18-25 21.8 (1.6) 24.4 (2.5) 0.021*
10-17 14.0 (2.9) 16.0 (4.2) 0.842
≥26 27.9 (1.3) 27.8 (2.3) 0.579
TMT
A sec 99.6 (83.4) 86.4 (49.4) 0.804
A errors 0.7 (1.1) 16.3 (57.5) 0.393
B sec 175.2 (116.1) 164.0 (72.4) 0.412
B errors 1.9 (1.6) 1.4 (1.8) 0.046*
(B-A) 75.5 (45.2) 77.6 (49.8) 0.262
Verbal fluency
Categorical (animals) 14.6 (5.4) 15.7 (6.9) 0.060
HAD
Depression 9.2 (4.8) 7.6 (3.7) 0.366
Anxiety 10.0 (5.2) 9.3 (5.1) 0.262
No (n=10)
MoCA
Global score 22.0 (5.7) 22.2 (7.4) 0.915
<26 19.0 (5.0) 18.1 (8.1) 1.000
18-25 21.8 (2.8) 22.0 (4.7) 0.396
10-17 15.8 (1.26) 13.0 (-) 0.317
≥26 27.4 (1.4) 27.0 (1.7) 0.831
TMT
A sec 94.4 (68.1) 92.6 (57.3) 0.917
A errors 0.7 (1.1) 0.4 (1.0) 0.152
B sec 173.9 (95.5) 157.8 (64.8) 0.235
B errors 2.1 (1.7) 2.0 (1.8) 0.271
(B-A) 79.5 (56.7) 65.1 (32.3) 0.452
Verbal fluency
Categorical (animals) 16.0 (7.7) 17.2 (7.5) 0.417
HAD
Depression 9.3 (5.6) 7.5 (4.8) 0.587
Anxiety 9.5 (4.4) 9.8 (5.1) 0.526

Abbreviations: MoCA, Montreal Cognitive Assessment; TMT, Trail Making Test; HAD, Hospital Depression and Anxiety Scale.

Notes: Wilcoxon test (Wilcoxon matched-pairs or Wilcoxon signed-rank test). *Significance level <0.05.