Table 3. Cognitive and neuropsychiatric data (baseline and after 6 months).
Cognitive intervention |
|
|
p-value |
---|---|---|---|
Yes (n=19) | |||
MoCA | |||
Global score | 22.1 (6.0) | 23.3 (5.3) | 0.022* |
<26 | 18.7 (5.0) | 21.4 (5.2) | 0.019* |
18-25 | 21.8 (1.6) | 24.4 (2.5) | 0.021* |
10-17 | 14.0 (2.9) | 16.0 (4.2) | 0.842 |
≥26 | 27.9 (1.3) | 27.8 (2.3) | 0.579 |
TMT | |||
A sec | 99.6 (83.4) | 86.4 (49.4) | 0.804 |
A errors | 0.7 (1.1) | 16.3 (57.5) | 0.393 |
B sec | 175.2 (116.1) | 164.0 (72.4) | 0.412 |
B errors | 1.9 (1.6) | 1.4 (1.8) | 0.046* |
(B-A) | 75.5 (45.2) | 77.6 (49.8) | 0.262 |
Verbal fluency | |||
Categorical (animals) | 14.6 (5.4) | 15.7 (6.9) | 0.060 |
HAD | |||
Depression | 9.2 (4.8) | 7.6 (3.7) | 0.366 |
Anxiety | 10.0 (5.2) | 9.3 (5.1) | 0.262 |
No (n=10) | |||
MoCA | |||
Global score | 22.0 (5.7) | 22.2 (7.4) | 0.915 |
<26 | 19.0 (5.0) | 18.1 (8.1) | 1.000 |
18-25 | 21.8 (2.8) | 22.0 (4.7) | 0.396 |
10-17 | 15.8 (1.26) | 13.0 (-) | 0.317 |
≥26 | 27.4 (1.4) | 27.0 (1.7) | 0.831 |
TMT | |||
A sec | 94.4 (68.1) | 92.6 (57.3) | 0.917 |
A errors | 0.7 (1.1) | 0.4 (1.0) | 0.152 |
B sec | 173.9 (95.5) | 157.8 (64.8) | 0.235 |
B errors | 2.1 (1.7) | 2.0 (1.8) | 0.271 |
(B-A) | 79.5 (56.7) | 65.1 (32.3) | 0.452 |
Verbal fluency | |||
Categorical (animals) | 16.0 (7.7) | 17.2 (7.5) | 0.417 |
HAD | |||
Depression | 9.3 (5.6) | 7.5 (4.8) | 0.587 |
Anxiety | 9.5 (4.4) | 9.8 (5.1) | 0.526 |
Abbreviations: MoCA, Montreal Cognitive Assessment; TMT, Trail Making Test; HAD, Hospital Depression and Anxiety Scale.
Notes: Wilcoxon test (Wilcoxon matched-pairs or Wilcoxon signed-rank test). *Significance level <0.05.