Table 2.
Demographic data for PD with LDCT over and under 30% improvement.
| Variable | PD LDCT ≤ 30% (n = 21) | PD LDCT > 30% (n = 16) | p value |
|---|---|---|---|
| Age (y) | 65 [47, 78] | 67 [49, 87] | 0.591 |
| No. of men/women (%) | 12/9 (57.1, 42.9) | 10/6 (62.5, 37.5) | 1.000 |
| Age at symptom onset (y) | 57 [39, 71] | 57.5 [39, 84] | 0.771 |
| Age at time of diagnosis (y) | 61 [44, 73] | 60.5 [39, 84] | 0.976 |
| Disease duration after onset of symptoms (y) | 7 [4, 21] | 11 [3, 16] | 0.528 |
| Disease duration after diagnosis (y) | 5 [2, 12] | 7.5 [3, 13] | 0.076 |
| Education (y) | 17 [7, 24] | 15 [9.5, 20] | 0.042 |
| MoCA score | 27 [24, 30] | 27 [20, 30] | 0.596 |
PD LDCT ≤30%, PD acute levodopa challenge test with a change less than or equal to 30% improvement of UPDRS III; PD LDCT >30%, PD acute levodopa challenge test with more than 30% improvement of UPDRS III; MoCA, Montreal Cognitive Assessment. If participants had ≤12 years of education one point were added to the total MoCA score if < 30 to correct for education effects as recommended by the original validation study [9]. Three PD and three controls had ≤12 years of education and all three PD had 1 point added to their total score but only one control due to a score below 30. The median scores of MoCA for PD groups divided after the measured effect were both 27 (p 0.596). All values are reported as the median (minimum, maximum) or absolute frequency (relative frequency in %).