Supplemental Table 1. The EORTC QLQ C-30/OES-18 version three questionnaire English version.
| During the past week | Not at all | A little | Quite a bit | Very much | |
|---|---|---|---|---|---|
| 200. | Do you have trouble doing strenuous activities, like carrying a heavy shopping bag or a suitcase | 1 | 2 | 3 | 4 |
| 201. | Do you have trouble taking a long walk | 1 | 2 | 3 | 4 |
| 202. | Do you have trouble taking a short walk outside of the house | 1 | 2 | 3 | 4 |
| 203. | Do you have need to stay in bed or a chair during the day | 1 | 2 | 3 | 4 |
| 204. | Do you have need help with eating, dressing, washing yourself or using the toilet | 1 | 2 | 3 | 4 |
| During the past week | |||||
| 205. | Were you limited in doing either your work or other daily activities? | 1 | 2 | 3 | 4 |
| 206. | Were you limited in pursuing your hobbies or other leisure time activities? | 1 | 2 | 3 | 4 |
| 207. | Were you short of breath? | 1 | 2 | 3 | 4 |
| 208. | Have you had pain? | 1 | 2 | 3 | 4 |
| 209. | Did you need to rest? | 1 | 2 | 3 | 4 |
| 210. | Have you had trouble sleeping? | 1 | 2 | 3 | 4 |
| 211. | Have you felt weak? | 1 | 2 | 3 | 4 |
| 212. | Have you lacked appetite? | 1 | 2 | 3 | 4 |
| 213. | Have you felt nauseated? | 1 | 2 | 3 | 4 |
| 214. | Have you vomited? | 1 | 2 | 3 | 4 |
| 215. | Have you been constipated? | 1 | 2 | 3 | 4 |
| During past week | |||||
| 216. | Have you had diarrhoea? | 1 | 2 | 3 | 4 |
| 217. | Were you tired? | 1 | 2 | 3 | 4 |
| 218. | Did pain interfere with your daily activities? | 1 | 2 | 3 | 4 |
| 219. | Have you had difficulty in concentrating on things, like reading a newspaper or watching television? | 1 | 2 | 3 | 4 |
| 220. | Did you feel tense? | 1 | 2 | 3 | 4 |
| 221. | Did you worry? | 1 | 2 | 3 | 4 |
| 222. | Did you feel irritable? | 1 | 2 | 3 | 4 |
| 223. | Did you feel depressed? | 1 | 2 | 3 | 4 |
| 224. | Have you had difficulty remembering things? | 1 | 2 | 3 | 4 |
| 225. | Has your physical condition or medical treatment interfered with your family life? | 1 | 2 | 3 | 4 |
| 226. | Has your physical condition or medical treatment interfered with your social activities? | 1 | 2 | 3 | 4 |
| 228. | Has your physical condition or medical treatment caused you financial difficulties? | 1 | 2 | 3 | 4 |
| 229. | For the following questions please circle the number between 1 and 7 that best applies to you How would you rate your overall health during the past week? 1 Very poor 2 3 4 5 6 7 Excellent |
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| 230. | How would you rate your overall quality of life during the past week? 1 Very poor 2 3 4 5 6 7 Excellent |
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| EORTC QLQ OES-18 | |||||
| During the past week | Not at all | A little | Quite a bit | Very much | |
| 601. | Could you eat solid food? | 1 | 2 | 3 | 4 |
| 602. | Could you eat liquidised or soft food? | 1 | 2 | 3 | 4 |
| 603. | Could you drink liquids? | 1 | 2 | 3 | 4 |
| 604. | Have you had trouble with swallowing your saliva? | 1 | 2 | 3 | 4 |
| 605. | Have you choked when swallowing | 1 | 2 | 3 | 4 |
| 606. | Have you had trouble enjoying your meals? | 1 | 2 | 3 | 4 |
| 607. | Have you felt full up too quickly? | 1 | 2 | 3 | 4 |
| 608. | Have you had trouble with eating? | 1 | 2 | 3 | 4 |
| 609. | Have you had trouble with eating in front of other people? | 1 | 2 | 3 | 4 |
| 610. | Have you had a dry mouth? | 1 | 2 | 3 | 4 |
| 611. | Have you had problems with your sense of taste? | 1 | 2 | 3 | 4 |
| 612. | Have you had trouble with coughing? | 1 | 2 | 3 | 4 |
| 613. | Have you had trouble with talking | 1 | 2 | 3 | 4 |
| 614. | Have you had acid indigestion or heartburn? | 1 | 2 | 3 | 4 |
| 615. | Have you had trouble with acid or bile coming into your mouth? | 1 | 2 | 3 | 4 |
| 616. | Have you had pain when you eat? | 1 | 2 | 3 | 4 |
| 617. | Have you had pain in your chest? | 1 | 2 | 3 | 4 |
| 618. | Have you had pain in your stomach? | 1 | 2 | 3 | 4 |