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. 2024 Jan 15;18:1654. doi: 10.3332/ecancer.2024.1654

Table 2. 1L treatment of patients with ROS1 positive NSCLC.

1L treatment for metastatic disease n = 68 (%)
A. ROS1 TKI 38 (55.88%)
1. Upfront ROS1 TKI
a. Crizotinib
b. Entrectinib
c. Ceritinib
2. Chemotherapy followed by ROS1 TKI
3. Chemo-immunotherapy followed by ROS1 TKI
4. Chemo-bevacizumab followed by ROS1 TKI
5. EGFR TKI + ROS1 TKI
12 (17.65%)
9 (13.24%)
1 (1.47%)
2 (2.94%)
21 (30.88%)
3(4.41%)
1 (1.47%)
1 (1.47%)
B. Other than ROS1 TKI 30 (44.12%)
1. Chemotherapy only (Pemetrexed-carboplatin)
2. Chemo-bevacizumab
3. EGFR TKI
4. No treatment
20 (29.41%)
1 (1.47%)
8 (11.76%)
1 (1.47%)