Table 2. 1L treatment of patients with ROS1 positive NSCLC.
| 1L treatment for metastatic disease | n = 68 (%) |
|---|---|
| A. ROS1 TKI | 38 (55.88%) |
| 1. Upfront ROS1 TKI a. Crizotinib b. Entrectinib c. Ceritinib 2. Chemotherapy followed by ROS1 TKI 3. Chemo-immunotherapy followed by ROS1 TKI 4. Chemo-bevacizumab followed by ROS1 TKI 5. EGFR TKI + ROS1 TKI |
12 (17.65%) 9 (13.24%) 1 (1.47%) 2 (2.94%) 21 (30.88%) 3(4.41%) 1 (1.47%) 1 (1.47%) |
| B. Other than ROS1 TKI | 30 (44.12%) |
| 1. Chemotherapy only (Pemetrexed-carboplatin) 2. Chemo-bevacizumab 3. EGFR TKI 4. No treatment |
20 (29.41%) 1 (1.47%) 8 (11.76%) 1 (1.47%) |