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Types of AI and Clinical Features
| Primary AI | Central AI | HPA axis suppression | |
|---|---|---|---|
| Cortisol | Low | Low | Low |
| DHEAS | Low | Low | Low |
| ACTH | High | Low | Low |
| Aldosterone | Low | Varies | Varies |
| Renin | High | Varies | Varies |
| CST cortisol | Low | Low | Low |
| Actions | Determine etiology | Check pituitary axes | Can recover function |
AI, adrenal insufficiency; HPA, hypothalamic-pituitary-adrenal; DHEAS, dehydroepiandrosterone-sulfate; ACTH, adrenocorticotropic hormone; CST, cosyntropin stimulation test.
