Fig. 2. Electrophysiological properties of CD151^high/low ACMs and VCMs.

a Representative APs recorded in CD151^high/low ACMs from AIC-CMs and CD151^high/low VCMs from VIC-CMs. b Electrophysiology measurements of Vmax, APA, and MDP in CD151^high ACMs (n = 16) and CD151^low ACMs (n = 17) from three independent differentiation experiments. Data are presented as mean ± SEM. Statistical analysis was conducted using an unpaired two-tailed t test. **p < 0.01 and ****p < 0.0001. c The proportions of AIC-CMs with atrial (ACM; APD30/90 < 0.3, Vmax > 10), ventricular-like (VCM-like; APD30/90 ≥ 0.3, Vmax > 10), and nodal-like APs (Vmax ≤ 10) in CD151^high ACMs (n = 16) and CD151^low ACMs (n = 17). d Electrophysiology measurements of APD30, APD50, and APD90 in CD151^high VCMs (n = 15) and CD151^low VCMs (n = 16) from three independent differentiation experiments. Data are presented as mean ± SEM. Statistical analysis was conducted using an unpaired two-tailed t test. *p < 0.05. (See also Fig. S3b). e The proportions of VIC-CMs with ventricular (VCM), atrial-like (ACM-like), and nodal-like APs in CD151^high (n = 15) and CD151^low VCMs (n = 18). The criteria are described in (c).