Table 3.
Differences in Haematological neoplasm related deaths for Sarcoidosis patients and the general Spanish population by lineage.
| Neoplasm-related deaths N (%) |
Mean age (years), (SD) |
||||||
|---|---|---|---|---|---|---|---|
| Non-sarcoidosis | Sarcoidosis | p | Non-sarcoidosis | Sarcoidosis | p | OR (95% CI)a | |
| Haematological | 12,362 (8.9) | 16 (20.5) | 0.001 | 71.9 (15.5) | 63.6 (12.5) | 0.032 | 2.64 (1.52–4.59) |
| Malign haematological | 11,993 (8.6) | 14 (18.4) | 0.006 | 71.7 (15.6) | 62.32 (12.8) | 0.023 | 2.30 (1.28–4.11) |
| Lymphoma | 4241 (3) | 7 (9.2) | 0.008 | 70.7 (14.7) | 56.9 (14) | 0.013 | 3.09 (1.42–6.73) |
| Hodgkin Lymphoma | 261 (0.2) | 0 | 1 | 65.5 (18.4) | – | – | – |
| Non-Hodgkin Lymphoma | 3980 (2.9) | 7 (9.2) | 0.006 | 71 (14.4) | 56.9 (14) | 0.009 | 3.33 (1.53–7.25) |
| B cell lineage | 3541 (2.5) | 5 (6.6) | 0.044 | 71.7 (14.2) | 59 (10.1) | 0.046 | 2.62 (1.06–6.50) |
| T/NK cell lineage | 439 (0.3) | 2 (2.6) | 0.024 | 65.6 (14.6) | 51.5 (26.1) | 0.174 | 7.88 (1.92–32.29) |
| Leukemia | 4627 (3.3) | 4 (5.3) | 0.322 | 70.2 (18.1) | 70.5 (10.8) | 0.972 | 1.50 (0.55–4.10) |
| Myeloid lineage | 3193 (2.3) | 2 (2.6) | 0.694 | 71.2 (15.5) | 61.5 (0.71) | 0.377 | 1.09 (0.27–4.45) |
| Lymphoid lineage | 1005 (0.7) | 1 (1.3) | 0.423 | 64.7 (24.3) | 83 | 0.452 | 1.56 (0.22–11.30) |
| Multiple myeloma | 2163 (1.6) | 2 (2.6) | 0.342 | 74 (11) | 68 (5.7) | 0.445 | 1.70 (0.42–6.93) |
| Myelodisplastic syndrome | 885 (0.6) | 1 (1.3) | 0.384 | 78.7 (12) | 55 | 0.049 | 2.37 (0.33–17.16) |
| Others | 77 (0.1) | 0 | 1 | 71 (17.1) | – | – | – |
| Unknown behaviour | 369 (0.3) | 2 (2.6) | 0.018 | 79 (10.5) | 73 | 0.419 | 11.88 (2.88–49.02) |
| Myeloproliferative disorders | 242 (0.2) | 1 (1.3) | 0.124 | 78.4 (10.1) | 75 | 0.592 | |
| Others | 127 (0.1) | 1 (1.3) | 0.067 | 80.2 (11.3) | 73 | 0.528 | - |
SD: Standard deviation, OR: Odds ratio, CI: Confidence interval.
Values in bold highlight statistically significant differences.
After adjustment for age, sex, alcohol and tobacco consumption.