Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Feb 28;147(1):48. doi: 10.1007/s00401-024-02711-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — Ingenuity pathway analysis (IPA) on control and TSC primary astrocytes cultures. a. Volcano plot showing the differentially expressed proteins (DEPs) (p value ≤ 0.05) between control (n = 6) and TSC (n = 6) primary culture astrocytes. A total of 76 proteins were found to be upregulated and 71 downregulated in TSC compared to control astrocytes. b. Top-ranked 40 enriched canonical pathways predicted by IPA (p value ≤ 0.05). The size of each point is proportional to the number of differentially expressed proteins present in the pathway, while the intensity of the color indicates the p value of the predicted canonical signaling pathways