Table 4.

Association between rs2839698 and rs217727 variants and obesity in different models (allelic and genotypes)

rsID	Models	OR (95% CI) (1)	P-value (1)	FDR q-Value (1)	OR (95% CI) (2)	P-value (2)	FDR q-value (2)
rs2839698	Allele model T vs. C	3.29 (2.67–4.05)	<0.0001	<0.0001	3.38 (2.74–4.17)	<0.0001	<0.0001
	Co-dominant TT vs. CC CT vs. CC	14.02 (8.39–23.43)	<0.0001	<0.0001	15.74 (9.18–26.99)	<0.0001	<0.0001
		9.45 (6.36–14.04)	<0.0001	<0.0001	9.4 (6.31–14.01)	<0.0001	<0.0001
	Dominant TT+CT vs. CC	10.32 (7.03–15.17)	<0.0001	<0.0001	10.46 (7.1–15.43)	<0.0001	<0.0001
	Recessive TT vs. CT+CC	3.02 (2–4.56)	<0.0001	<0.0001	3.26 (2.14–4.97)	<0.0001	<0.0001
	Over dominant TT+CC vs. CT	0.31 (0.23–0.41)	<0.0001	<0.0001	0.32 (0.24–0.43)	<0.0001	<0.0001
rs217727	Allele model T vs. C	0.6 (0.48–0.75)	<0.0001	<0.0001	0.61 (0.49–0.77)	0.00002	0.00002
	Co-dominant TT vs. CC CT vs. CC	0.23 (0.11–0.46)	<0.0001	<0.0001	0.23 (0.11–0.48)	0.00007	0.00003
		0.65 (0.49–0.87)	0.0042	0.0008	0.67 (0.5–0.9)	0.007	0.001
	Dominant TT+CT vs. CC	0.58 (0.44–0.77)	0.0002	0.00006	0.6 (0.45–0.79)	0.0004	0.0001
	Recessive TT vs. CT+CC	0.27 (0.13–0.55)	0.0003	0.00007	0.28 (0.14–0.57)	0.0004	0.0001
	Over dominant TT+CC vs. CT	1.33 (1–1.76)	0.047	0.008	1.3 (0.98–1.73)	0.06	0.01

Unadjusted Odds Ratios (plus Confidence Intervals) and adjusted Odds Ratios by gender are reported for effect alleles and genotypes