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. 2024 Feb 28;20(2):31. doi: 10.1007/s11306-024-02088-0

Table 2.

Differential protein expression levels between the 22q11.2DS and the TD groups

Sr # Name Description logFC AveExpr P value adj.P.Val Formula Uniprot Peptide Ion Type
1 HEP2/ SERPIND1 Heparin cofactor 2 − 0.29567 7.38517 0 0.00128 C46H63N11O10 P05546 FAFNLYR [M + 2H]2+  protein
2 HEP2/ SERPIND1 Heparin cofactor 2 − 0.24434 7.6289 0.00002 0.02712 C44H77N13O15 P05546 TLEAQLTPR [M + 2H]2+  protein
3 HEP2/ SERPIND1 Heparin cofactor 2 − 0.12795 7.60783 0.00007 0.04036 C35H64N10O10 P05546 LNILNAK [M + 2H]2+  protein
4 IGHM Immunoglobulin heavy constant mu − 0.32915 7.96117 0.0001 0.04036 C43H69N11O10 P01871 n (Lim et al., 2019) VSVFVPPR [M + 2H]2+  protein
5 IGHM Immunoglobulin heavy constant mu − 0.35531 8.4965 0.00011 0.04036 C66H112N20O27 P01871 QVGSGVTTDQVQAEAK [M + 2H]2+  protein
6 IGHM Immunoglobulin heavy constant mu − 0.32583 8.09937 0.00011 0.04036 C36H58N10O9 P01871 GFPSVLR [M + 1H]1+  Protein
7 PLF4 Platelet factor 4 − 0.43806 7.49934 0.00014 0.04036 C47H82N12O14 P02776 HITSLEVIK [M + 2H]2+  Protein
8 FLNA Filamin-A − 0.39502 7.43397 0.00017 0.04036 C62H99N17O22 P21333 ANLPQSFQVDTSK [M + 2H]2+  Protein
9 IGHM Immunoglobulin heavy constant mu − 0.28069 8.6498 0.00018 0.04036 C66H111N15O17 P01871 NVPLPVIAELPPK [M + 2H]2+  Protein
10 ACTB Actin, cytoplasmic 1 − 0.58166 7.73957 0.00019 0.04036 C142H223N37O44S1 P60709 TTGIVMDSGDGVTHTVPIYEGYALPHAILR [M + 4H]4+  Protein
11 IGJ Immunoglobulin J chain − 0.29129 7.1815 0.0002 0.04036 C55H88N16O26 P01591 SSEDPNEDIVER [M + 2H]2+  Protein
12 IGHM Immunoglobulin heavy constant mu − 0.36074 7.46153 0.00021 0.04036 C70H109N19O22S1 P01871 YVTSAPMPEPQAPGR [M + 2H]2+  Protein
13 IGHM Immunoglobulin heavy constant mu − 0.37507 7.70203 0.00024 0.04385 C82H124N16O19 P01871 VFAIPPSFASIFLTK [M + 2H]2+  Protein
14 IGHM Immunoglobulin heavy constant mu − 0.34688 8.07107 0.00025 0.04452 C58H96N14O18 P01871 YAATSQVLLPSK [M + 2H]2+  Protein
15 TYB4 Thymosin beta-4 − 0.49529 7.4072 0.00031 0.05055 C65H109N17O24 P62328 NPLPSKETIEQEK [M + 3H]3+  Protein
16 HEP2/ SERPIND1 Heparin cofactor 2 − 0.32954 7.35303 0.00032 0.05055 C48H78N12O16 P05546 SVNDLYIQK