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. 2023 Nov 4;23(1):271–286. doi: 10.1007/s10237-023-01774-7

Table 2.

Mechanical model parameters. It is noticed that in the current model formulation only the ratio (and not the absolute values) between kXB and δm is required. Some of the fitted parameters were restrained between specific ranges of values: 0.13 hw 0.40, 1.0 λz 1.5, 1.0 kω 1.5, 0.1 r.v. uPS 10.0 r.v., 0.1 r.v. kXBδm 10.0 r.v., 0.1 r.v. kACmax 10.0 r.v. where r.v. is the reference value from Murtada et al. (2016)

Parameter Description Value
Geometry
Ro (cm) Load-free outer radius 0.0110, 0.0126 - assumed
hw (-) Load-free thickness-medium radius ratio 0.367 - fitted
λz (-) Axial stretch 1.364 - fitted
kω (-) Circumferential pre-stretch 1.373 - fitted
Passive response
c0 (dyne cm-2) Material constant 9.1633 · 104 - fitted
c1 (dyne cm-2) Material constant 3.15 · 104 - from Murtada and Holzapfel (2014)
c2 (-) Material constant 0.646 - fitted
ϕ () Fibres orientation angle 0.0 - assumed
Active response
NCF (cm-2) Number of CF per unit area 2.44 · 1010 - from Murtada et al. (2016)
LSMC (cm) SMC length 0.01 - from Murtada et al. (2016)
Lm (cm) Myosin filament length 3.0 · 10-5 - from  Murtada et al. (2016)
uPS (cm) Average elongation caused by power-stroke 1.424 · 10-6 - fitted
kXBδm (dyne cm-2) Cross-bridge elastic stiffness per distance between myosin monomers 8.166777 · 106 - fitted
u¯fsopt(-)(-) Normalized optimal filament sliding 1.490 · 10-2 - fitted
sfo (cm) Filament overlap scaling factor 5.870 · 10-7 - fitted
kACmax (dyne cm-1) Actin cortex stiffness scaling factor 1.004 · 101 - fitted
nAC (-) Actin cortex activation function coefficient 4.156 - fitted
KAC (-) Actin cortex activation function coefficient 10.201 - fitted