Table 2.
Mechanical model parameters. It is noticed that in the current model formulation only the ratio (and not the absolute values) between and is required. Some of the fitted parameters were restrained between specific ranges of values: 0.13 0.40, 1.0 1.5, 1.0 1.5, 0.1 r.v. 10.0 r.v., 0.1 r.v. 10.0 r.v., 0.1 r.v. 10.0 r.v. where r.v. is the reference value from Murtada et al. (2016)
| Parameter | Description | Value |
|---|---|---|
| Geometry | ||
| (cm) | Load-free outer radius | 0.0110, 0.0126 - assumed |
| (-) | Load-free thickness-medium radius ratio | 0.367 - fitted |
| (-) | Axial stretch | 1.364 - fitted |
| (-) | Circumferential pre-stretch | 1.373 - fitted |
| Passive response | ||
| (dyne cm-2) | Material constant | 9.1633 · 104 - fitted |
| (dyne cm-2) | Material constant | 3.15 · 104 - from Murtada and Holzapfel (2014) |
| (-) | Material constant | 0.646 - fitted |
| (∘) | Fibres orientation angle | 0.0 - assumed |
| Active response | ||
| (cm-2) | Number of CF per unit area | 2.44 · 1010 - from Murtada et al. (2016) |
| (cm) | SMC length | 0.01 - from Murtada et al. (2016) |
| (cm) | Myosin filament length | 3.0 · 10-5 - from Murtada et al. (2016) |
| (cm) | Average elongation caused by power-stroke | 1.424 · 10-6 - fitted |
| (dyne cm-2) | Cross-bridge elastic stiffness per distance between myosin monomers | 8.166777 · 106 - fitted |
| (-) | Normalized optimal filament sliding | 1.490 · 10-2 - fitted |
| (cm) | Filament overlap scaling factor | 5.870 · 10-7 - fitted |
| (dyne cm-1) | Actin cortex stiffness scaling factor | 1.004 · 101 - fitted |
| (-) | Actin cortex activation function coefficient | 4.156 - fitted |
| (-) | Actin cortex activation function coefficient | 10.201 - fitted |