Table 1.

Corticosteroids in oral lichen planus.

Drug	Mechanism of Action	Indications	Method and Dose	Side Effect
Triamcinolone acetonide	1.Aanti-cell proliferlation 2.Causes eosinophils and lymphocytes to trigger programmed cell death or apoptosis; reduces neutrophil apoptosis 3.Induces vasoconstriction and reduce blood flow to the lesion 4.Usually inhibits the maturation, differentiation and proliferation of all immune cells	Topical application: non-erosive/mild-to-moderate erosive OLP patients Subcutaneous injection: unresponsive or poorly responsive to topical medications	Topical application: Balm: topical application:0.1% TA paste, tid (gums and palate) Suspension(liquid):1mg/ml, t.i.d (Suitable for coated mucous membranes) Subcutaneous injection: Topical injection: 0.2-0.4ml(10mg/ml) TA once a week, 2-3 weeks	1.Dysbiosis 2.Systemic complications
Betamethasone		Erosive oral lichen planus topical application	500 mg betamethasone tablets dissolved in 10-15 ml of water for mouthwash, 4 times daily.
Dexamethasone		OLP with extensive intraoral lesions topical application	0.1mg/ml, 5ml, 3 times/day
Clobetasol propionate		Erosive oral lichen planus topical application	Clobetasol ointment(0.05%), 3-4 times/day
Prednisolone		Systemic administration: for severe multifocal lesions with large erosions	Systemic administration: Adult dose of 40 mg daily (first 5 days), 10-20 mg daily (6-10 days)