Table 2:
Incidence rate ratios (95% CI) for one-unit increases in QCHAT-10 score associated with maternal obesity and diabetes during pregnancy1
| Relative increase in QCHAT-10 score (IRR 95% CI) | |
|---|---|
| Single exposure * | |
| Obesity 2 | |
| Underweight (BMI >18.5kg/m2) | 1.06 (0.98–1.14) |
| Overweight (BMI 25–29.9kg/m2) | 1.03 (0.99–1.05) |
| Obese Class 1 (BMI 30–34.9kg/m2) | 1.07 (1.04–1.11) |
| Obese Class 2 (BMI 35.0–39.9 kg/m2) | 1.16 (1.12–1.21) |
| Obese Class 3 (BMI >40.0 kg/m2) | 1.26 (1.19–1.32) |
| Diabetes 3 | |
| Preexisting diabetes | 1.13 (1.06–1.21) |
| GDM ≤ 26 weeks | 1.10 (1.05–1.17) |
| GDM > 26 weeks | 1.04 (0.99–1.09) |
| Multiple exposure, mutually adjusted + | |
| Obesity | |
| Underweight (BMI >18.5kg/m2) | 1.06 (0.98–1.14) |
| Overweight (BMI 25–29.9kg/m2) | 1.02 (0.99–1.05) |
| Obese Class 1 (BMI 30–34.9kg/m2) | 1.07 (1.03–1.10) |
| Obese Class 2 (BMI 35.0–39.9 kg/m2) | 1.15 (1.11–1.20) |
| Obese Class 3 (BMI >40.0 kg/m2) | 1.24 (1.18–1.30) |
| Diabetes | |
| Preexisting diabetes | 1.08 (1.00–1.16) |
| GDM diagnosed at ≤ 26 gestational weeks | 1.07 (1.01–1.13) |
| GDM diagnosed at > 26 gestational weeks | 1.02 (0.97–1.07) |
1
From negative binomial regression adjusted for birth year, maternal age, parity, maternal race/ethnicity, maternal educational qualifications, history of comorbidity, income (per 10k), and child’s sex
2
Reference category is Normal BMI (18.5–24.9 kg/m2)
3
Reference category is No Diabetes
*
Not adjusted for the other maternal pregnancy exposure
+
Simultaneously adjusted for the other maternal pregnancy exposure